Advanced visualisation, integration and biological interpretation of -omics data Second edition 7 - 9 November 2011 Wageningen, The Netherlands Organised by the Graduate Schools VLAG and WIAS, in co-operation with the Centre for Bioinformatics of the Erasmus MC, Rotterdam 
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Background
Over the last years microarray technology has become one of the principal platform technologies for the high-throughput analysis of biological systems, with applications ranging from plant sciences and ecology to nutrition and biomedical research. For instance, microarray expression profiling and post-genomics data analysis has made it possible to delineate subgroups of cancer patients with poor and good prognosis, important steps towards personalized medicine. Microarray profiling followed by gene set enrichment analysis has made it possible to show that in planta overexpression of a single fungal protein induces plant gene expression profiles that are more similar to those induced upon infection by microbial pathogens. Much of the success of gene expression profiling has resulted from pathway analysis and reconstruction of gene regulatory networks. Nowadays, diverse in silico tools are available to transform gene expression data into protein-protein interaction networks or gene regulatory networks, and to integrate multiple pathways. These software packages typically use not only molecular interaction data but also gene annotation and literature information. Use of such tools makes it possible to achieve a better representation of the available data and to infer a meaningful biological context, thereby advancing the integration of expression data into other experimental work such as histology and proteomics. These approaches also work very well in top-down systems biology experiments.
Target group
PhD students or Postdocs working on genomics (microarray) projects and with handling of ~omics datasets.
Course aim
During this technical course, attendants will become acquainted with several popular in silico tools for microarray data analyses and visualization. Focus will be on data visualization. Applications and concepts from different research areas including organismal development, pathology, nutrition and medical biology will be introduced. The presentations will represent data on plants, animals and humans to show the general applicability of array data visualization and the underlying concepts. Computer practicals will teach the attendants the basic and more advanced handling of large datasets. After this course, attendants will have a good overview of the approaches and software that lead to successful microarray data handling, and how to integrate the results into related studies and experiments. They will also learn how to use and develop concepts in -omics studies.
Course design
The program will be a combination of lectures (mornings) and computer practicals (afternoon).
Programme topics
Course coordinators
Other faculty
Date & duration
The course will be held from Monday 7 - Wednesday 9 November 2011.
Study load
The study load of this course is 0.8 ECTS credits.
Language
The course will be conducted in English.
Location & accommodation
Lectures and practicals will be given at the University campus. A number of hotel rooms have been blocked at Hof van Wageningen for course participants, but only until 26th September 2011. Accommodation costs are € 80 (single room; incl. breakfast, excl. Tax)) and € 98.50 (double room; incl. breakfast, excl. Tax) per night. For information visit www.hofvanwageningen.nl.
Participants have to book their own hotel room by sending an e-mail to info@hofvanwageningen.nl.
Please mention booking code "Adv-Omics '11".
Contact information
For question regarding the course content please contact Guido Hooiveld (for VLAG PhD students), Guido.Hooiveld@wur.nl or Peter van Baarlen (for WIAS PhD students), Peter.vanBaarlen@wur.nl.
For organisational matters please contact Ingeborg van Leeuwen-Bol:
phone: +31 317 486108,
e-mail: Ingeborg.vanLeeuwen-Bol@wur.nl
Please register by completing the course registration form.
Registration is closed!
Note: to be able to fill in the course registration form, you need an account. To create an account, please click the link above. Don't forget to fill in the course registration form after creating your account.
Registration is based on the ‘first come, first serve’ principle, so register as soon as possible, but before 6 October 2011. The maximum number of participants is 18.
After 6 October 2011 you will be notified of acceptance of your registration and you will be sent instructions for payment and further information.
The course fee (which includes materials, lunches and coffee/tea during breaks, but does not cover accommodation) depends on the participant's affiliation:
| VLAG PhD students | € 150,- |
| PhD students | € 300,- |
| University staff/ Non -Profit organisations | € 600,- |
| Industry/ For -Profit | € 1200,- |
Click on the photos (courses 2011 and 2009) to enlarge them.
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