Project list research - research areaA: Sustainable production

A1 - Bio (techno) logical production routes

List of ongoing PhD projects (as of 15 June 2010).
In order to contact the respective PhD students (or supervisors) you are referred to the website of the university/institute where the research is done (see participating groups).

PhD student S. Al-Attar (Sinan), Microbiology, WU
Project titleRNA-based immunity in bacteria.
Supervisors Prof. J. van der Oost, Microbiology, WU
Dr. S.J.J. Brouns, Microbiology, WU
 
PhD student R.J. Boesten (Rolf), Microbiology, WU
Project titleInteraction between commensal bifidobacteria and diet and human intestinal tract: An integrated genomes approach towards gut health.
Supervisors Prof. W.M. de Vos, Microbiology, WU
Dr. F.H.J. Schuren, TNO Quality of Life
Dr. E.E. Vaughan, Microbiology, WU
 
PhD student H. van Bokhorst-van de Veen (Hermien), NIZO food research
Project titleEnhancing health-impact culture delivery.
Supervisors Prof. M. Kleerebezem, NIZO food research
Dr. P.A. Bron, NIZO food research
 
PhD student C.D. Ceapa (Corina), Microbiology, WU
Project titleImpact of genomic diversity of a probiotic on its immunomodulation effects.
Supervisors Prof. M. Kleerebezem, NIZO food research
Dr. J. Knol, Danone Research
 
PhD student A. Chavaroche (Anaïs), Food & Biobased Research, WUR
Project titleDirected evolution of glycosaminoglycan synthases.
Supervisors Prof. G. Eggink, Bioprocess Engineering, WU
 
PhD student J.B.J.H. van Duuren (Joost), Food & Biobased Research, WUR
Project titleCofactor-dependent whole-cell biotransformation of a model compound by Pseudomonas putida KT2440.
Supervisors Prof. G. Eggink, Bioprocess Engineering, WU
Dr. A.E. Mars, Food & Biobased Research, WUR
Dr. J. Wery, TNO Quality of Life
 
PhD student O. Ercan (Onur), NIZO food research
Project titleZero growth of lactic acid bacteria; plant-microbe interactions and increased heterogeneity.
Supervisors Prof. M. Kleerebezem, NIZO food research
Prof. J. Hugenholtz, NIZO food research
 
PhD student E.V. Eremeeva (Elena), Biochemistry, WU
Project titleMolecular mechanism of an active photoprotein complex formation.
Supervisors Prof. A.J.W.G. Visser, Biochemistry, WU
Dr. W.J.H. van Berkel, Biochemistry, WU
Dr. E.S. Vysotski, Biophysics, RAS, Russia
Dr. S.V. Markova, Biophysics, RAS, Russia
 
PhD student P. Falcicchio (Pierpaolo), Microbiology, WU
Project titleIndustrially relevant heterocycles through biocatalysis cascades.
Supervisors Prof. J. van der Oost, Microbiology, WU
Dr. S.W.M. Kengen, Microbiology, WU
 
PhD student N.A.L. Flahaut (Nicolas), Microbiology, WU
Project titleProduction and delivery of bioingredients: Modelling of flavour fomation from amino acids.
Supervisors Prof. W.M. de Vos, Microbiology, WU
Dr. P.J. Schaap
Dr. L. Sijtsma, Food & Biobased Research, WUR
Dr. D.E. Martens, Bioprocess Engineering, WU
 
PhD student A. da Fonseca e Sousa (Claudia), Bioprocess Engineering, WU
Project titleOxygen production in photobioreactors: a biological approach.
Supervisors Prof. R.H. Wijffels, Bioprocess Engineering, WU
Dr. M.G.J. Janssen, Bioprocess Engineering, WU
Dr. M. Vermuë, Bioprocess Engineering, WU
 
PhD student J. Gerritsen (Coline), Microbiology, WU
Project titleCRIB, an essential bacterium to protect us against infectious complications?
Supervisors Prof. W.M. de Vos, Microbiology, WU
Dr. H. Smidt, Microbiology, WU
Dr. G.T. Rijkers, Pediactrics and surgery, UMCU
 
PhD student A. Goel (Anisha), Microbiology, WU
Project titleOptimizing growth rate, biomass and product formation of Lactococcus lactis by a systems biology approach.
Supervisors Prof. W.M. de Vos, Microbiology, WU
Prof. B. Teusink, Molecular Cell Physiology, VU
Dr. D. Molenaar, Molecular Cell Physiology, VU
 
PhD student M.D. Golinska (Monika), Physical Chemistry and Colloid Science, WU
Project titleModular protein polymers.
Supervisors Prof. M.A. Cohen Stuart, PCC, WU
Dr. F.A. de Wolf, Food & Biobased Research, WUR
 
PhD student R.J.A. Gosselink (Richard), Valorisation of Plant Production Chains, WU
Project titleLignin as the renewable resource for the future.
Supervisors Prof. J.P.M. Sanders, Valorisation of Plant Production Chains, WU
Prof. G. Gellerstedt, EMT, Royal Institute of Technology, Stockholm
Dr. J.E.G. van Dam, Food & Biobased Research, WUR
Dr. E.L. Scott, Valorisation of Plant Production Chains, WU
Dr. E. de Jong, Avantium
 
PhD student R. Heshof (Ruud), Systems and Synthetic Biology, WU
Project titleNovel Enzyme tools for production of functional oleochemicals from unsaturated lipids (ERA -NOEL).
Supervisors Prof. W.M. de Vos, Microbiology, WU
Dr. L.H. de Graaff
Prof. V.A.F. Martins dos Santos, Microbiology, WU
 
PhD student J.J.J. van der Hooft (Justin), Biochemistry, WU
Project titleMetabolite identification: Combining high resolution UPLC-FTMS and HPLC-SPE-NMR in phytonutrients metabolomics.
Supervisors Prof. S.C. de Vries, Biochemistry, WU
Prof. R.J. Bino, Applied Sciences, TU Delft
Dr. J.J.M. Vervoort, Biochemistry, WU
Dr. C.H. de Vos, PRI, WUR
 
PhD student F. Hugenholtz (Floor), Microbiology, WU
Project titleGut microbiomics of SCFA metabolism.
Supervisors Prof. M. Kleerebezem, NIZO food research
Prof. V.A.F. Martins dos Santos
Dr. H. Smidt, Microbiology, WU
 
PhD student V.C.L. de Jager (Victor), Microbiology, WU
Project titleBiodiversity, genotype-phenotype analysis and functional dynamics of Lactic Acid Bacteria in complex microbial consortia.
Supervisors Prof. M. Kleerebezem, NIZO food research
Prof. R.J. Siezen, NIZO food research
Dr. S.A.F.T. van Hijum, NIZO food research
 
PhD student M.M. Jore (Matthijs), Microbiology, WU
Project titleKilling the messenger - a novel prokaryotic immune system based on RNA interference.
Supervisors Prof. J. van der Oost, Microbiology, WU
Dr. S.J.J. Brouns, Microbiology, WU
 
PhD student S. Kochappi Rajan (Sukithar), Microbiology, WU
Project titleGenome mining and expression profiling of intestinal commensals.
Supervisors Prof. W.M. de Vos, Microbiology, WU
Dr. H. Smidt, Microbiology, WU
 
PhD student R.K.P. Kuipers (Remko), Systems and Synthetic Biology, WU
Project title3D structure based multiple sequence alignments applied to rational enzyme design and DNA diagnostics.
Supervisors Prof. V.A.F. Martins dos Santos,
Prof. G. Vriend, Centre for Molecular and Biomolecular Informatics, NCMLS, RUN
Dr. P.J. Schaap
 
PhD student W. Kuit (Wouter), Food & Biobased Research, WUR
Project titleMicrobial chemical stress, analysis and engineering.
Supervisors Prof. G. Eggink, Bioprocess Engineering, WU
Dr. A.M. Lopez Contreras, Food & Biobased Research, WUR
 
PhD student O. Kutahya (Oylum), Microbiology, WU
Project titlePopulation dynamics of a mixed dairy starter.
Supervisors Prof. M. Kleerebezem, NIZO food research
Dr. E.J. Smid, NIZO food research
 
PhD student I. Lamot (Ischa), Valorisation of Plant Production Chains, WU
Project titleRedox cofactor regeneration in microorganisms.
Supervisors Prof. J.P.M. Sanders, Valorisation of Plant Production Chains, WU
Prof. J. van der Oost, Microbiology, WU
Dr. R.A. Weusthuis, Food & Biobased Research, WUR
 
PhD student S. Lindhoud (Simon), Biochemistry, WU
Project titleVisualisation and characterization of protein folding events in vivo.
Supervisors Prof. S.C. de Vries, Biochemistry, WU
Dr. C.P.M. van Mierlo, Biochemistry, WU
 
PhD student E. van Loenen (Esther), Biochemistry, WU
Project titleBrassinolide signaling in Arabidopsis procambial cells.
Supervisors Prof. S.C. de Vries, Biochemistry, WU
Dr. C. Albrecht, Biochemistry, WU
Dr. J.W. Borst, Biochemistry, WU
 
PhD student A. Marasabessy (Ahmad), Valorisation of Plant Production Chains, WU
Project titleMicrobial modification of Jatropha curcas press cake for energy and feed application.
Supervisors Prof. J.P.M. Sanders, Valorisation of Plant Production Chains, WU
Dr. R.A. Weusthuis, Food & Biobased Research, WUR
Dr. M.A. Moeis, Institut Teknologi Bandung, Indonesia
 
PhD student P. Meeuwse (Petra), Bioprocess Engineering, WU
Project titleMicrobial biomass conversion to transport fuels.
Supervisors Prof. J. Tramper, Bioprocess Engineering, WU
Dr. A. Rinzema, Bioprocess Engineering, WU
 
PhD student S. Menschel (Sven), NIZO food research
Project titleModelling peptide utilisation and growth of lactic acid bacteria.
Supervisors Prof. J. Hugenholtz, NIZO food research
Prof. M. Kleerebezem, NIZO food research
 
PhD student S. Montersino (Stefania), Biochemistry, WU
Project titleBiocatalytic exploitation of monooxygenases.
Supervisors Prof. S.C. de Vries, Biochemistry, WU
Dr. W.J.H. van Berkel, Biochemistry, WU
 
PhD student K.J.M. Mulders (Kim), Bioprocess Engineering, WU
Project titleIncreased production of pigments in micro algae.
Supervisors Prof. R.H. Wijffels, Bioprocess Engineering, WU
Dr. D.E. Martens, Bioprocess Engineering, WU
Ir. P.P. Lamers, Bioprocess Engineering, WU
 
PhD student J. Omony (Jimmy), Systems and Control Group, WU
Project titleGeneNet: System dynamic analysis of gene networks in fungal systems.
Supervisors Prof. G. van Straten, Systems and Control Group, WU
Prof. W.M. de Vos, Microbiology, WU
Dr. A.J.B. van Boxtel, Systems and Control Group, WU
Dr. L.H. de Graaff
 
PhD student J.M. Pimenta Ferreira de Oliveira (José Miguel), Microbiology, WU
Project titleFunctional genomics analysis of the secretion pathway in Aspergillus niger.
Supervisors Prof. J. van der Oost, Microbiology, WU
Dr. L.H. de Graaff
 
PhD student J.G.J. Raedts (John), Microbiology, WU
Project titleDirected evolution of glycosaminoglycan synthases and glycosaminoglycan modifying enzymes.
Supervisors Prof. J. van der Oost, Microbiology, WU
Dr. S.W.M. Kengen, Microbiology, WU
 
PhD student V.J.B. Ruigrok (Vincent), Microbiology, WU
Project titleExploring the boundaries for existence and detection of extraterrestrial life.
Supervisors Prof. J. van der Oost, Microbiology, WU
Prof. P. Ehrenfreund, Mathematics and natural sciences, Lincoln University, USA
Dr. H. Smidt, Microbiology, WU
 
PhD student S. Salim (Sina), Bioprocess Engineering, WU
Project titleHarvesting of algae for oil extraction.
Supervisors Prof. R.H. Wijffels, Bioprocess Engineering, WU
Dr. M. Vermuë, Bioprocess Engineering, WU
 
PhD student K.J. Schippers (Klaske), Bioprocess Engineering, WU
Project titleImmortalized sponge cell culture.
Supervisors Prof. R.H. Wijffels, Bioprocess Engineering, WU
Prof. J. van der Oost, Microbiology, WU
Dr. D.E. Martens, Bioprocess Engineering, WU
Dr. S.A. Pomponi, Harbor Branch Oceanographic Institution, USA
 
PhD student R. Schipperus (Roelof), Food & Biobased Research, WUR
Project titleExpression screening and synthesis methods for protein polymer genes assembled from newly designed segments (EXSPANDS).
Supervisors Prof. G. Eggink, Bioprocess Engineering, WU
Dr. F.A. de Wolf, Food & Biobased Research, WUR
 
PhD student J.R. van Seters (Janneke), Bioprocess Engineering, WU
Project titleThe influence of adaptive digital learning material on learning effectiveness of individual students.
Supervisors Prof. J. Tramper, Bioprocess Engineering, WU
Prof. M.J. Goedhart, UOCG, RuG
Dr. M.A. Ossevoort, UOCG, RuG
Dr. J.E. Wellink, Molecular Biology, WU
 
PhD student M.A.J. Siemerink (Marco), Microbiology, WU
Project titleRevival of butanol production by Clostridia.
Supervisors Prof. W.M. de Vos, Microbiology, WU
Prof. J. van der Oost, Microbiology, WU
Dr. S.W.M. Kengen, Microbiology, WU
 
PhD student P. Sierocinski (Pawel), Microbiology, WU
Project titleResponses to environmental change in sulfolobales.
Supervisors Prof. J. van der Oost, Microbiology, WU
Prof. W.M. de Vos, Microbiology, WU
 
PhD student P.M. Slegers (Ellen), Systems and Control Group, WU
Project titleFor efficient, robust and flexible algae plants; an advanced scenario study approach.
Supervisors Prof. G. van Straten, Systems and Control Group, WU
Prof. R.H. Wijffels, Bioprocess Engineering, WU
Dr. A.J.B. van Boxtel, Systems and Control Group, WU
 
PhD student M. aan den Toorn (Marije), Biochemistry, WU
Project titleProtein complex isolation: a new approach to identify genes involved in plant development and pathogenesis.
Supervisors Prof. S.C. de Vries, Biochemistry, WU
Dr. C.P.M. van Mierlo, Biochemistry, WU
Dr. R. Boer, IRB, Barcelona
 
PhD student A.K. Trilling (Anke Kristin), Organic Chemistry, WU
Project titleDevelopment of technologies to organize antibodies on surfaces.
Supervisors Prof. H. Zuilhof, Organic Chemistry, WU
Dr. M.J. Beekwilder, PRI, WUR
 
PhD student C.V. Vejrazka (Carsten), Bioprocess Engineering, WU
Project titleResponse of microalgae to fluctuating light in photobioreactors: A model approach.
Supervisors Prof. R.H. Wijffels, Bioprocess Engineering, WU
Dr. M.G.J. Janssen, Bioprocess Engineering, WU
 
PhD student P. Vossenberg (Petra), Bioprocess Engineering, WU
Project titleChemoenzymatic peptide synthesis.
Supervisors Prof. J. Tramper, Bioprocess Engineering, WU
Prof. M.A. Cohen Stuart, PCC, WU
Dr. H.H. Beeftink, Bioprocess Engineering, WU
 
PhD student J. Walther (Jasper), Microbiology, WU
Project titleMicroarray analysis to unravel Microbial Metabolism.
Supervisors Prof. W.M. de Vos, Microbiology, WU
Prof. J. van der Oost, Microbiology, WU
Dr. S.W.M. Kengen, Microbiology, WU
 
PhD student E.R. Westra (Edze), Microbiology, WU
Project titleCRISPR based defence in prokaryotes against foreign DNA - how does it work?
Supervisors Prof. J. van der Oost, Microbiology, WU
Dr. S.J.J. Brouns, Microbiology, WU
 
PhD student R. van Wielink (Rutger), Bioprocess Engineering, WU
Project titleDevelopment of a high yielding process for the next generation avian influenza vaccines.
Supervisors Prof. R.H. Wijffels, Bioprocess Engineering, WU
Prof. R.J.M. Moormann, Centraal Veterinair Instituut, WUR
Dr. M.M. Harmsen, Centraal Veterinair Instituut, WUR
Dr. D.E. Martens, Bioprocess Engineering, WU